Institutional repository



Laboratory location

Sugimoto Campus

Mail Address

E-mail address

Degree 【 display / non-display

  • Osaka University -  Doctor of Medicine

Research Areas 【 display / non-display

Cell biology

Research Career 【 display / non-display

  • Development of novel method for generation of monoclonal antibodies

    (Individual) Project Year :


    Keyword in research subject:  monoclonal antibody

Association Memberships 【 display / non-display

  • Japan Society for Cell Biology

Awards & Honors 【 display / non-display

  • CSF


Current Career 【 display / non-display

  • Osaka City University   Graduate School of Engineering   Applied Chemistry and Bioengineering Course   Professor  

Graduate School 【 display / non-display


    Osaka University  Graduate School, Division of Medicine 

Graduating School 【 display / non-display


    Osaka Prefecture University   Faculty of Engineering   Applied chemistry


Published Papers 【 display / non-display

  • EB1-binding-myomegalin protein complex promotes centrosomal microtubules functions

    Bouguenina Habib, Salaun Daniele, Mangon Aurelie, Muller Leslie, Baudelet Emilie, Camoin Luc, Tachibana Taro, Cianferani Sarah, Audebert Stephane, Verdier-Pinard Pascal, Badache Ali



  • A statistical image analysis framework for pore-free islands derived from heterogeneity distribution of nuclear pore complexes

    Mimura Yasuhiro, Takemoto Satoko, Tachibana Taro, Ogawa Yutaka, Nishimura Masaomi, Yokota Hideo, Imamoto Naoko

    SCIENTIFIC REPORTS  7 2017.11  [Refereed]


  • Crystal Structure and Characterization of Novel Human Histone H3 Variants, H3.6, H3.7, and H3.8

    Taguchi Hiroyuki, Xie Yan, Horikoshi Naoki, Maehara Kazumitsu, Harada Akihito, Nogami Jumpei, Sato Koichi, Arimura Yasuhiro, Osakabe Akihisa, Kujirai Tomoya, Iwasaki Takeshi, Semba Yuichiro, Tachibana Taro, Kimura Hiroshi, Ohkawa Yasuyuki, Kurumizaka Hitoshi

    BIOCHEMISTRY  56 ( 16 ) 2184 - 2196 2017.04  [Refereed]


  • Septin 9_i2 is downregulated in tumors, impairs cancer cell migration and alters subnuclear actin filaments

    Verdier-Pinard P., Salaun D., Bouguenina H., Shimada S., Pophillat M., Audebert S., Agavnian E., Coslet S., Charafe-Jauffret E., Tachibana T., Badache A.

    SCIENTIFIC REPORTS  7 2017.03  [Refereed]


  • Flocculation of Real Sewage Sludge Using Poly-gamma-glutamic Acid Produced by <it>Bacillus</it> sp Isolated from Soil

    Liu Tao, Yamashita Kyouhei, Fukumoto Yoshihiro, Tachibana Taro, Azuma Masayuki

    公益社団法人 化学工学会 JOURNAL OF CHEMICAL ENGINEERING OF JAPAN  50 ( 3 ) 201 - 206 2017.03  [Refereed]

     View Summary

    <p>To promote the use of sewage sludge on farmland, a flocculant compatible with agricultural application is required. In general, an inorganic flocculant such as aluminium sulfate is used at large sewage disposal plants. However, there is concern that aluminium accumulates when it is returned to farmland, and therefore a biodegradable rather than an inorganic flocculant is required. To obtain biodegradable flocculants produced by microorganisms, the latter were isolated from soils and sewage sludges, and the flocculation activity of the culture broths was evaluated. Here, real sewage sludge was used for the evaluation because practical use was regarded as an important consideration. As a result, two strains, V13 and RK14, were selected and identified as <i>Bacillus megaterium</i> and <i>Bacillus licheniformis</i>, respectively. It was also found that flocculation was caused by poly-γ-glutamic acid (γ-PGA). γ-PGA from RK14 cells had considerably higher molecular weight than commercial γ-PGA, and the enantiomeric composition differed from that of γ-PGA from other <i>B. licheniformis</i>. To obtain mutants with high γ-PGA productivity, RK14 cells were treated with ethyl methanesulfonate, and a mutant (RK14-46) was selected. The culture medium suitable for γ-PGA production by RK14-46 cells was totally different from that by RK-14 cells. The γ-PGA production reached 21.1 g/L when RK14-46 cells were cultured in the optimum semi-synthetic medium at 30°C for 2 d. Furthermore, the combination of γ-PGA obtained from RK14-46 cells and chitosan, a cationic flocculant, was very effective for flocculation of real sewage sludge.</p>

    DOI CiNii

display all >>

Review Papers (Misc) 【 display / non-display

  • Rapid and efficient method for production of monoclonal antibodies

    Taro Tachibana, Tomohiko Yoshimi, Takaomi Fukuhara

    15 ( 1 ) 68 - 70 2012

  • Generation of rat monoclonal antibodies

    21   25 - 28 2006

  • Function of methylglyoxal as a post-translationl modifer


  • Molecular organization and function of postsynaptic density(PSD)

    45 ( 3 ) 522 - 531 2000

  • Mechanism of nuclear localization of proteins

    27 ( 4 ) 42 - 45 1995

display all >>


Other educational activity and Special note 【 display / non-display

  • Contribution to University-wide Cross-training program


  • Contribution to FD activities



Theme of Possible Research Exchange 【 display / non-display

  • Production of monoclonal antibodies

    Request for collaborative research : The private sector, such as other institutions

    Type of research exchange : Technical consultation, Consignment study, Collaborative research

    Keyword : Antibody


Foreigner acceptance 【 display / non-display

  • Academic year : 2017

     View Details

    Number of International Students