YOKOYAMA Hisayo

写真a

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Title

Associate Professor

Laboratory location

Sugimoto Campus

Mail Address

E-mail address

Research Interests 【 display / non-display

energy metabolism, frailty, metabolic syndrome, health promotion, diabetes, cognitive function, falls, exercise

Research Career 【 display / non-display

  • The effect of exercise on defecation and gut microbiota related to the motivation for physical activity.

    (Individual) Project Year :

    2016.09
     
     

    Keyword in research subject:  microbiota

  • The effect of nasal insulin administration on fat oxidation during exercise

    (Individual) Project Year :

    2015.10
     
     

    Keyword in research subject:  nasal insulin administration

  • The effects of brain insulin signaling and exercise on incretin secretion, gastric emptying and appetite

    (Individual) Project Year :

    2014.08
     
     

    Keyword in research subject:  intranasal insulin administration

  • The effects of exercise on muscle strength and bone metabolism in maintenance hemodialysis patients -the contribution of myostatin, a peptide derived from skeletal muscle-

    (Collaboration in Japan) Project Year :

    2014.08
     
     

    Keyword in research subject:  intradialysis exercise

  • The effects of dual-task exercise training on cognitive function and plasma amyloid be-ta protein 42 level in the healthy elderly

    (Collaboration in Japan) Project Year :

    2014.04
     
     

    Keyword in research subject:  cognitive function, elderly, exercise

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Association Memberships 【 display / non-display

  • Japanese Society of Physical Fitness and Sports Medicine

  • The Japanese Society of Internal Medicine

  • The physiological society of Japan

  • Japan Diabetes Society

  • Japanese Society of Clinical Sports Medicine

Committee Memberships 【 display / non-display

  • 2020.10
    -
    2024.11

    Japan Society of Clinical Sports Medicine   delegate

Current Career 【 display / non-display

  • Osaka City University   Research Center for Urban Health and Sports   Associate Professor  

  • Osaka City University   Center for Health Science Innovation   Researcher  

  • Osaka City University   Center of Education and Research for Disaster (CERD)   Researcher  

  • Osaka City University   Graduate School of Medicine   Basic Medicine Course   Associate Professor  

Graduate School 【 display / non-display

  •  
    -
    2005

    Osaka City University  Graduate School, Division of Medicine 

Graduating School 【 display / non-display

  •  
    -
    1999

    Osaka City University   Faculty of Medicine  

 

Published Papers 【 display / non-display

  • Eating Perception, Nutrition Knowledge and Body Image among Para-Athletes: Practical Challenges in Nutritional Support

    Miwako Deguchi, Hisayo Yokoyama, Nobuko Hongu, Hitoshi Watanabe, Akira Ogita, Daiki Imai, Yuta Suzuki and Kazunobu Okazaki

    Nutrients  13 ( 9 ) 3120 2021.09  [Refereed]

     View Summary

    Limited information exists on dietary practices in para-athletes. The aim of this study was to clarify the actual situation of para-athletes’ dietary practice and to sort out the factors (i.e., eating perception, nutrition knowledge, and body image), that may hinder their dietary practices, and explored the practical challenges in nutritional support and improving nutrition knowledge for para-athletes. Thirty-two Japanese para-athletes (22 men) and 45 collegiate student athletes without disabilities (27 men) participated in the online survey. The questionnaire included demographic characteristics, eating perception, dietary practices, and nutrition knowledge. The Japanese version of the body appreciation scale was used to determine their body image. Para-athletes who answered that they knew their ideal amount and way of eating showed significantly higher body image scores
    (r = 0.604, p < 0.001). However, mean score for nutrition knowledge of para-athletes were significantly lower than collegiate student athletes (19.4 ± 6.8 vs. 24.2 ± 6.1 points, p = 0.001). Both groups
    did not identify a dietitian as the source of nutrition information or receiving their nutrition advice.
    The results indicate para-athletes have unique eating perceptions and inadequate nutrition knowledge. Future interventions are needed to examine nutritional supports and education in relation to the role of dietitians.

    DOI

  • Masticatory ability is associated with bone mineral density in young women with normal bone mineral density

    Emiko Morita, Hisayo Yokoyama, Ryosuke Takeda, Yamashina Yoshihiro, Eriko Kawai, Tomoe Fukumura

    The Japanese Journal of Physical Fitness and Sports Medicine  69 ( 4 ) 317 - 325 2020.08  [Refereed]

     View Summary

    We examined the relationship between masticatory ability and bone mineral density (BMD) and the role of muscle strength in those relationships in 156 female university students. Masticatory ability was assessed using a color-changeable chewing gum method. The BMD of the calcaneus was measured using quantitative ultrasonography and represented by a T-score, the standard deviation (SD) from the mean BMD of young
    adults. Body composition, grip strength, physical activity level, and daily nutrient intake were also assessed. Osteopenia, defined as the T-score < ‒1.0 SD, was present in 43 participants (27.6%). There was no significant relationship between masticatory ability
    (ΔE) and T-score in all participants. In participants with normal BMD (T-score ≧ ‒1.0 SD:the normal BMD group), masticatory ability significantly correlated to BMD (r = 0.289, p = 0.002). There was significant correlation between ΔE and grip strength neither in all
    participants nor in either group, although the grip strength in the normal BMD group was greater than that in the participants with osteopenia (the low BMD group) (p = 0.039). Physical activity level was positively correlated to the total daily energy intake (r = 0.193,
    p = 0.041) only in the normal BMD group. The present results suggest that masticatory ability is associated with BMD in young females with normal BMD, but the role of muscle strength in those relationships remains unclear. Meanwhile, there was no relationship between masticatory ability and BMD in young individuals with lower BMD.

    DOI

  • Increase in diastolic blood pressure induced by fragrance inhalation of grapefruit essential oil is positively correlated with muscle sympathetic nerve activity

    Kawai Eriko, Takeda Ryosuke, Ota Akemi, Morita Emiko, Imai Daiki, Suzuki Yuta, Yokoyama Hisayo, Ueda Shin-ya, Nakahara Hidehiro, Miyamoto Tadayoshi, Okazaki Kazunobu

    JOURNAL OF PHYSIOLOGICAL SCIENCES  70 ( 1 )  2020.01  [Refereed]

    DOI

  • Increase in diastolic blood pressureh induced by fragrance inhalation of grapefruit essential oil is positively correlated with muscle sympathetic nerve activity(和訳中)

    Kawai Eriko, Takeda Ryosuke, Ota Akemi, Morita Emiko, Imai Daiki, Suzuki Yuta, Yokoyama Hisayo, Ueda Shin-ya, Nakahara Hidehiro, Miyamoto Tadayoshi, Okazaki Kazunobu

    (一社)日本生理学会 The Journal of Physiological Sciences  70   1 of 11 - 11 of 11 2020.01  [Refereed]

  • Exercise Habit is Associated with Lower Fall Risks among Elderly People Living in Urban Areas

    Hisayo Yokoyama, Hitoshi Watanabe, Kazumi Saito, Ayane Shibata, Yuta Suzuki, Daiki Imai, Kazunobu Okazaki, Akira Ogita

    Age and Ageing  48 ( Suppl 4 )  2019.12  [Refereed]

     View Summary

    In the present superaged society that has limited financial resources for efficient health care for the elderly population, fall prevention is an urgent issue. The present study examined the relationship between exercise habit and fall risks among elderly people living in an urban area. A total of 1,014 elderly people (age: 65–89 years) living in Osaka City were enrolled in this study and assigned to 5 different age groups. The motor abilities of the participants were evaluated by the Functional Reach Test (FRT) and the Timed Up and Go (TUG) test, with the cutoff value for fall risk set at 25 cm and 13.5 s, respectively. Exercise habit (≤1 h, 1–2 h, or ≥2 h per week), history of recent falls, and anxiety about falling were also assessed using a questionnaire modified from the checklist by the Ministry of Health, Labour and Welfare of Japan. The results of the FRT and TUG tests were increasingly poorer in higher age groups. History of recent falls and anxiety about falling were also more frequent in higher age groups (all p < .05). The prevalence of exercise habits was similar among the age groups. In the age groups >75 years, there was an association between exercise habit and a decrease in fall risks, based on the FRT results (all p < .05). The mean FRT value of the participants with the greatest exercise habit was equivalent to that of the generation 10 years younger with the lowest exercise habit. There was an association between exercise habit and decreased anxiety about falling (p = .003), but not with a history of recent falls. Our results suggest that exercise should be promoted among elderly people living in urban areas to contribute to fall prevention.

    DOI

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Books etc 【 display / non-display

  • 透析運動療法~健康長寿を実現するために~ 各論 1. 運動療法と病態 9)糖尿病における運動療法.

    (Part: Single Work )

    医薬ジャーナル社  2016.11

  • 透析運動療法~健康長寿を実現するために~ 各論 2. 運動療法の評価法 1)心肺運動負荷試験(CPX).

    (Part: Single Work )

    医薬ジャーナル社  2016.11

  • 糖尿病腎症の治療のポイント 第V章 腎症5期:透析療法期の治療のポイント 3. 運動療法.

    (Part: Single Work )

    医薬ジャーナル社  2016.08

  • いまさら訊けない!CKD患者 栄養・運動療法の考えかた,やりかたQ&A IV 栄養に関連した病態の評価 Q3. 認知機能障害はどう評価するのがよいですか?CKD患者では認知機能と栄養状態は関連しますか?.

    (Part: Single Work )

    中外医学社  2016.06

  • Evaluation of insulin resistance in diabetes: standard protocol for a euglycemic-hyperinsulinemic clamp using an artificial pancreas. Musculoskeletal Disease Associated with Diabetes Mellitus.

    (Part: Joint Work )

    Springer  2015.12

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Review Papers (Misc) 【 display / non-display

  • Exercise capacity of patients with type 2 diabetes: a mini review of clinical findings.

    J Endocrinol Diab  2 ( 4 ) 1 - 5 2015.12

  • Exercise capacity of patients with type 2 diabetes: a mini review of clinical findings.

    J Endocrinol Diab  2 ( 4 ) 1 - 5 2015.12  [Refereed]  [Invited]

  • 私は本当に「食べすぎ」なのか? 糖尿病にまつわるさまざまな誤解

    横山 久代

    大阪市立大学都市健康・スポーツ研究センター 公立大学法人大阪市立大学健康・スポーツ科学  8   21 - 26 2014.03  [Refereed]  [Invited]

  • 新時代の糖尿病学 病因・診断・治療研究の進歩 糖尿病の疫学・病態・診断学の進歩 糖尿病検査学の進歩 インスリン分泌能の評価 アルギニン負荷試験

    絵本正憲,横山久代,西沢良記

    日本臨床増刊 4 新時代の糖尿病学  66 ( 2 ) 189 - 192 2008  [Refereed]  [Invited]

Conference Activities & Talks 【 display / non-display

  • Pilot study on nutrition knowledge and fooding behavior of para-athletes

    Miwako Deguchi, Hisayo Yokoyama, Nobuko Hongu, Hitoshi Watanabe, Akira Ogita, Daiki Imai, Yuta Suzuki, Kazunobu Okazaki

    The 76th Japanese Society of Physical Fitness and Sports Medicine  2021.09  Japanese Society of Physical Fitness and Sports Medicine

  • Influence of mental fatigue accompanied with cold exposure on subsequent endurance exercise performance

    The 76th Japanese Society of Physical Fitness and Sports Medicine  2021.09  Japanese Society of Physical Fitness and Sports Medicine

  • Mental stress do not impair aerobic exercise performance after whole body cold exposure

    Daiki Imai, Ryosuke Takeda, Eriko Kawai, Kosuke Saho, Akemi Ota, Emiko Morita, Yuta Suzuki, Hisayo Yokoyama, Kazunobu Okazaki

    The 97th Annual Meeting of the Physiological Society of Japan  (Beppu City)  2020.03 

     View Summary

    Whole body cold exposure or mental load applied before exercise is known to decrease exercise performance. However the effects of simultaneous application of these stresses on exercise performance remain unknown. We investigated the effects of simultaneous application of whole body cold exposure and mental load on aerobic exercise performance compared with cold exposure alone.
    Seven healthy young male participants underwent the stroop color word test (500 stimuli/set × 2) as mental stress trial (MS), while watched a documentary DVD as non-stress trial (NS) during 60 min of cold exposure using a water-perfused suit. Water temperature in the suit was maintained at 15˚C for 10 min then at 10˚C. They undressed the suit then performed a cycling test at 80% VO2max to the exhaustion. Esophageal and skin temperatures (Tes and Tsk, respectively), plasma adrenaline ([Ad]p), noradrenaline ([Nord]p), and cortisol ([Cortisol]p) concentrations, and subjective fatigue index (SFI) were measured before and immediately after mental stress and exercise. Exercise duration was evaluated as aerobic performance.
    We found that Tsk was lower after cooling than baseline, while Tes remained unchanged. Tsk and Tes were not different between trials. A significant effect of interaction (time × trial) was found on [Ad]p (p=0.023), [Nord]p (p=0.047), and SFI (p=0.040), while not on [Cortisol]p. Exercise duration was not different between trials (p=0.762).
    In conclusion, the simultaneous application of mental load accompanied with whole body cold exposure exacerbated tiredness via the enhanced sympathetic nerve activity compared with cold exposure alone, while did not impair aerobic exercise performance.

  • Exercise Habit Is Associated with Lower Fall Risks among Elderly People Living in Urban Areas

    Yokoyama H, Watanabe H, Saito K, Shibata A, Suzuki Y, Imai D, Okazaki K, Ogita A

    1st World Congress on Falls and Postural Stability  (Kuala Lumpur, Malaysia)  2019.12 

     View Summary

    In the present superaged society that has limited financial resources for efficient health care for the elderly population, fall prevention is an urgent issue. The present study examined the relationship between exercise habit and fall risks among elderly people living in an urban area. A total of 1,014 elderly people (age: 65–89 years) living in Osaka City were enrolled in this study and assigned to 5 different age groups. The motor abilities of the participants were evaluated by the Functional Reach Test (FRT) and the Timed Up and Go (TUG) test, with the cutoff value for fall risk set at 25 cm and 13.5 s, respectively. Exercise habit (≤1 h, 1–2 h, or ≥2 h per week), history of recent falls, and anxiety about falling were also assessed using a questionnaire modified from the checklist by the Ministry of Health, Labour and Welfare of Japan. The results of the FRT and TUG tests were increasingly poorer in higher age groups. History of recent falls and anxiety about falling were also more frequent in higher age groups (all p < .05). The prevalence of exercise habits was similar among the age groups. In the age groups >75 years, there was an association between exercise habit and a decrease in fall risks, based on the FRT results (all p < .05). The mean FRT value of the participants with the greatest exercise habit was equivalent to that of the generation 10 years younger with the lowest exercise habit. There was an association between exercise habit and decreased anxiety about falling (p = .003), but not with a history of recent falls. Our results suggest that exercise should be promoted among elderly people living in urban areas to contribute to fall prevention.

  • Effects of dual stress of whole body cold exposure and mental load on endurance exercise performance

    Daiki Imai, Ryosuke Takeda, Eriko Kawai, Kosuke Saho, Akemi Ota, Emiko Morita, Yuta Suzuki, Hisayo Yokoyama, Kazunobu Okazaki

    The Journal of Physical Fitness and Sports Medicine  2019.11  (一社)日本体力医学会

     View Summary

    [Aims] Whole body cold exposure decreases endurance exercise performance however the effects of additional mental fatigue remain unknown. We tested the hypothesis that dual stress of whole body cold exposure and mental stress decreases endurance exercise performance compared with cold exposure alone. [Methods] Healthy young male participants performed the stroop color word test (500 stimuli/set × 2) as mental stress trial (MS) or watched a documentary DVD as non-stress trial (NS) during 60 min of cold exposure using a water-perfused suit. Water temperature was maintained at 15˚C for 10 min then at 10˚C. They removed the suit then performed a cycling test at 80% VO2max to exhaustion. Esophageal and skin temperatures (Tes and Tsk, respectively), plasma adrenaline ([Ad]p), noradrenaline ([Nord]p), cortisol ([Cortisol]p) concentrations, and subjective fatigue index (SFI) were measured before and immediately after mental stress and exercise. Exercise duration was evaluated as endurance performance. [Results] Tes and Tsk were not different between trials. There were significant effect of interaction (time × trial) on [Ad]p (p=0.023), [Nord]p (p=0.047) concentration, and SFI (p=0.040), while not on [Cortisol]p. Exercise duration was not different between trials (p=0.762). [Conclusions] Dual stress of whole body cold exposure and mental stress exacerbated tiredness via the enhanced sympathetic nerve activity compared with cold exposure alone, while did not influence endurance exercise performance.

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Other external funds procured 【 display / non-display

  • The effects of dual-task exercise training on cognitive function and plasma amyloid be-ta protein 42 level in the healthy elderly

    System name: TIPNESS, Inc (Cooperative Research)  Representative

    Project Year :

    2014.03
    -
    2015.03

  • The contribution of myostatin related to the effects of exercise on bone metabolism in the elderly

    System name: TIPNESS, Inc (Cooperative Research)  Representative

    Project Year :

    2014.03
    -
    2015.03

  • The effects of dual-task exercise training on cognitive function and plasma amyloid be-ta protein 42 level in the healthy elderly

    System name: The 30th health science research grant for young investigator by Meiji Yasuda Life Foundation of Health and Welfare (Education/Research Fund Contributions)  Representative

    Project Year :

    2014.01
    -
    2015.03

 

Other educational activity and Special note 【 display / non-display

  • Improvement of educational methods

    (2021)

  • Improvement of educational methods

    (2020)

  • Improvement of educational methods

    (2018)

  • Contribution to FD activities

    (2018)

  • Contribution to FD activities

    (2017)

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Educational activity record 【 display / non-display

  • Academic year : 2021

     View Details

    Number of instructed the graduation thesis
    0
    Number of graduation thesis reviews
    0
    Number of instructed the Master course
    0
    Number of instructed the Doctoral course
    4
    Number of master's thesis reviews (chief)
    0
    Number of master's thesis reviews (vice-chief)
    0
    Number of doctoral thesis reviews (chief)
    0
    Number of doctoral thesis reviews (vice-chief)
    0
  • Academic year : 2020

     View Details

    Number of instructed the graduation thesis
    0
    Number of graduation thesis reviews
    0
    Number of instructed the Master course
    0
    Number of instructed the Doctoral course
    3
    Number of master's thesis reviews (chief)
    0
    Number of master's thesis reviews (vice-chief)
    0
    Number of doctoral thesis reviews (chief)
    0
    Number of doctoral thesis reviews (vice-chief)
    0
  • Academic year : 2019

     View Details

    Number of instructed the graduation thesis
    0
    Number of graduation thesis reviews
    0
    Number of instructed the Master course
    1
    Number of instructed the Doctoral course
    2
    Number of master's thesis reviews (chief)
    0
    Number of master's thesis reviews (vice-chief)
    0
    Number of doctoral thesis reviews (chief)
    0
    Number of doctoral thesis reviews (vice-chief)
    0
  • Academic year : 2018

     View Details

    Number of instructed the graduation thesis
    0
    Number of graduation thesis reviews
    0
    Number of instructed the Master course
    1
    Number of instructed the Doctoral course
    2
    Number of master's thesis reviews (chief)
    0
    Number of master's thesis reviews (vice-chief)
    0
    Number of doctoral thesis reviews (chief)
    0
    Number of doctoral thesis reviews (vice-chief)
    0
  • Academic year : 2017

     View Details

    Number of instructed the graduation thesis
    0
    Number of graduation thesis reviews
    0
    Number of instructed the Master course
    1
    Number of instructed the Doctoral course
    3
    Number of master's thesis reviews (chief)
    0
    Number of master's thesis reviews (vice-chief)
    0
    Number of doctoral thesis reviews (chief)
    0
    Number of doctoral thesis reviews (vice-chief)
    0

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Social Contribution 【 display / non-display

 

Foreigner acceptance 【 display / non-display

  • Academic year : 2016

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    Number of International Students
    1